A major locus controls local adaptation and adaptive life history variation in a perennial plant.
Identifieur interne : 001077 ( Main/Exploration ); précédent : 001076; suivant : 001078A major locus controls local adaptation and adaptive life history variation in a perennial plant.
Auteurs : Jing Wang [Suède, Norvège] ; Jihua Ding [Suède] ; Biyue Tan [Suède] ; Kathryn M. Robinson [Suède] ; Ingrid H. Michelson [Suède] ; Anna Johansson [Suède] ; Björn Nystedt [Suède] ; Douglas G. Scofield [Suède] ; Ove Nilsson [Suède] ; Stefan Jansson [Suède] ; Nathaniel R. Street [Suède] ; P R K. Ingvarsson [Suède]Source :
- Genome biology [ 1474-760X ] ; 2018.
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Abstract
BACKGROUND
The initiation of growth cessation and dormancy represent critical life-history trade-offs between survival and growth and have important fitness effects in perennial plants. Such adaptive life-history traits often show strong local adaptation along environmental gradients but, despite their importance, the genetic architecture of these traits remains poorly understood.
RESULTS
We integrate whole genome re-sequencing with environmental and phenotypic data from common garden experiments to investigate the genomic basis of local adaptation across a latitudinal gradient in European aspen (Populus tremula). A single genomic region containing the PtFT2 gene mediates local adaptation in the timing of bud set and explains 65% of the observed genetic variation in bud set. This locus is the likely target of a recent selective sweep that originated right before or during colonization of northern Scandinavia following the last glaciation. Field and greenhouse experiments confirm that variation in PtFT2 gene expression affects the phenotypic variation in bud set that we observe in wild natural populations.
CONCLUSIONS
Our results reveal a major effect locus that determines the timing of bud set and that has facilitated rapid adaptation to shorter growing seasons and colder climates in European aspen. The discovery of a single locus explaining a substantial fraction of the variation in a key life-history trait is remarkable, given that such traits are generally considered to be highly polygenic. These findings provide a dramatic illustration of how loci of large-effect for adaptive traits can arise and be maintained over large geographical scales in natural populations.
DOI: 10.1186/s13059-018-1444-y
PubMed: 29866176
PubMed Central: PMC5985590
Affiliations:
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Robinson</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Michelson, Ingrid H" sort="Michelson, Ingrid H" uniqKey="Michelson I" first="Ingrid H" last="Michelson">Ingrid H. 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Scofield</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:affiliation>Department of Ecology and Genetics, Evolutionary Biology, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Ecology and Genetics, Evolutionary Biology, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Uppsala Multidisciplinary Center for Advanced Computational Science, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Uppsala Multidisciplinary Center for Advanced Computational Science, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Nilsson, Ove" sort="Nilsson, Ove" uniqKey="Nilsson O" first="Ove" last="Nilsson">Ove Nilsson</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, 901 83, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, 901 83, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Jansson, Stefan" sort="Jansson, Stefan" uniqKey="Jansson S" first="Stefan" last="Jansson">Stefan Jansson</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Street, Nathaniel R" sort="Street, Nathaniel R" uniqKey="Street N" first="Nathaniel R" last="Street">Nathaniel R. Street</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Ingvarsson, P R K" sort="Ingvarsson, P R K" uniqKey="Ingvarsson P" first="P R K" last="Ingvarsson">P R K. Ingvarsson</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå, Sweden. par.ingvarsson@slu.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Present address: Department of Plant Biology, Uppsala BioCenter, Swedish University of Agricultural Sciences, PO Box 7080, 750 07, Uppsala, Sweden. par.ingvarsson@slu.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Present address: Department of Plant Biology, Uppsala BioCenter, Swedish University of Agricultural Sciences, PO Box 7080, 750 07, Uppsala</wicri:regionArea><wicri:noRegion>Uppsala</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2018">2018</date><idno type="RBID">pubmed:29866176</idno><idno type="pmid">29866176</idno><idno type="doi">10.1186/s13059-018-1444-y</idno><idno type="pmc">PMC5985590</idno><idno type="wicri:Area/Main/Corpus">000E03</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000E03</idno><idno type="wicri:Area/Main/Curation">000E03</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000E03</idno><idno type="wicri:Area/Main/Exploration">000E03</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">A major locus controls local adaptation and adaptive life history variation in a perennial plant.</title><author><name sortKey="Wang, Jing" sort="Wang, Jing" uniqKey="Wang J" first="Jing" last="Wang">Jing Wang</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå, Sweden. jingwang368@gmail.com.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Centre for Integrative Genetics, Department of Animal and Aquacultural Sciences, Faculty of Life Sciences, Norwegian University of Life Sciences, PO Box 5003, Ås, Norway. jingwang368@gmail.com.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Centre for Integrative Genetics, Department of Animal and Aquacultural Sciences, Faculty of Life Sciences, Norwegian University of Life Sciences, PO Box 5003, Ås</wicri:regionArea><wicri:noRegion>Ås</wicri:noRegion></affiliation></author><author><name sortKey="Ding, Jihua" sort="Ding, Jihua" uniqKey="Ding J" first="Jihua" last="Ding">Jihua Ding</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, 901 83, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, 901 83, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Tan, Biyue" sort="Tan, Biyue" uniqKey="Tan B" first="Biyue" last="Tan">Biyue Tan</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Stora Enso Biomaterials, 13104, Nacka, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Stora Enso Biomaterials, 13104, Nacka</wicri:regionArea><wicri:noRegion>Nacka</wicri:noRegion></affiliation></author><author><name sortKey="Robinson, Kathryn M" sort="Robinson, Kathryn M" uniqKey="Robinson K" first="Kathryn M" last="Robinson">Kathryn M. Robinson</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Michelson, Ingrid H" sort="Michelson, Ingrid H" uniqKey="Michelson I" first="Ingrid H" last="Michelson">Ingrid H. Michelson</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Johansson, Anna" sort="Johansson, Anna" uniqKey="Johansson A" first="Anna" last="Johansson">Anna Johansson</name><affiliation wicri:level="4"><nlm:affiliation>Wallenberg Advanced Bioinformatics Infrastructure, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Wallenberg Advanced Bioinformatics Infrastructure, Science for Life Laboratory, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Nystedt, Bjorn" sort="Nystedt, Bjorn" uniqKey="Nystedt B" first="Björn" last="Nystedt">Björn Nystedt</name><affiliation wicri:level="4"><nlm:affiliation>Wallenberg Advanced Bioinformatics Infrastructure, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Wallenberg Advanced Bioinformatics Infrastructure, Science for Life Laboratory, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Scofield, Douglas G" sort="Scofield, Douglas G" uniqKey="Scofield D" first="Douglas G" last="Scofield">Douglas G. Scofield</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:affiliation>Department of Ecology and Genetics, Evolutionary Biology, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Ecology and Genetics, Evolutionary Biology, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Uppsala Multidisciplinary Center for Advanced Computational Science, Uppsala University, Uppsala, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Uppsala Multidisciplinary Center for Advanced Computational Science, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Nilsson, Ove" sort="Nilsson, Ove" uniqKey="Nilsson O" first="Ove" last="Nilsson">Ove Nilsson</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, 901 83, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, 901 83, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Jansson, Stefan" sort="Jansson, Stefan" uniqKey="Jansson S" first="Stefan" last="Jansson">Stefan Jansson</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Street, Nathaniel R" sort="Street, Nathaniel R" uniqKey="Street N" first="Nathaniel R" last="Street">Nathaniel R. Street</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Ingvarsson, P R K" sort="Ingvarsson, P R K" uniqKey="Ingvarsson P" first="P R K" last="Ingvarsson">P R K. Ingvarsson</name><affiliation wicri:level="1"><nlm:affiliation>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå, Sweden. par.ingvarsson@slu.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå</wicri:regionArea><wicri:noRegion>Umeå</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Present address: Department of Plant Biology, Uppsala BioCenter, Swedish University of Agricultural Sciences, PO Box 7080, 750 07, Uppsala, Sweden. par.ingvarsson@slu.se.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Present address: Department of Plant Biology, Uppsala BioCenter, Swedish University of Agricultural Sciences, PO Box 7080, 750 07, Uppsala</wicri:regionArea><wicri:noRegion>Uppsala</wicri:noRegion></affiliation></author></analytic><series><title level="j">Genome biology</title><idno type="eISSN">1474-760X</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adaptation, Physiological (genetics)</term><term>Genes, Plant (genetics)</term><term>Genetic Loci (genetics)</term><term>Genetic Variation (genetics)</term><term>Genome, Plant (genetics)</term><term>Life History Traits (MeSH)</term><term>Phenotype (MeSH)</term><term>Plants (genetics)</term><term>Populus (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adaptation physiologique (génétique)</term><term>Caractéristiques du cycle biologique (MeSH)</term><term>Gènes de plante (génétique)</term><term>Génome végétal (génétique)</term><term>Locus génétiques (génétique)</term><term>Phénotype (MeSH)</term><term>Plantes (génétique)</term><term>Populus (génétique)</term><term>Variation génétique (génétique)</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Adaptation, Physiological</term><term>Genes, Plant</term><term>Genetic Loci</term><term>Genetic Variation</term><term>Genome, Plant</term><term>Plants</term><term>Populus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Adaptation physiologique</term><term>Gènes de plante</term><term>Génome végétal</term><term>Locus génétiques</term><term>Plantes</term><term>Populus</term><term>Variation génétique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Life History Traits</term><term>Phenotype</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Caractéristiques du cycle biologique</term><term>Phénotype</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>The initiation of growth cessation and dormancy represent critical life-history trade-offs between survival and growth and have important fitness effects in perennial plants. Such adaptive life-history traits often show strong local adaptation along environmental gradients but, despite their importance, the genetic architecture of these traits remains poorly understood.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>We integrate whole genome re-sequencing with environmental and phenotypic data from common garden experiments to investigate the genomic basis of local adaptation across a latitudinal gradient in European aspen (Populus tremula). A single genomic region containing the PtFT2 gene mediates local adaptation in the timing of bud set and explains 65% of the observed genetic variation in bud set. This locus is the likely target of a recent selective sweep that originated right before or during colonization of northern Scandinavia following the last glaciation. Field and greenhouse experiments confirm that variation in PtFT2 gene expression affects the phenotypic variation in bud set that we observe in wild natural populations.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>Our results reveal a major effect locus that determines the timing of bud set and that has facilitated rapid adaptation to shorter growing seasons and colder climates in European aspen. The discovery of a single locus explaining a substantial fraction of the variation in a key life-history trait is remarkable, given that such traits are generally considered to be highly polygenic. These findings provide a dramatic illustration of how loci of large-effect for adaptive traits can arise and be maintained over large geographical scales in natural populations.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29866176</PMID><DateCompleted><Year>2018</Year><Month>10</Month><Day>30</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>14</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1474-760X</ISSN><JournalIssue CitedMedium="Internet"><Volume>19</Volume><Issue>1</Issue><PubDate><Year>2018</Year><Month>06</Month><Day>04</Day></PubDate></JournalIssue><Title>Genome biology</Title><ISOAbbreviation>Genome Biol</ISOAbbreviation></Journal><ArticleTitle>A major locus controls local adaptation and adaptive life history variation in a perennial plant.</ArticleTitle><Pagination><MedlinePgn>72</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1186/s13059-018-1444-y</ELocationID><Abstract><AbstractText Label="BACKGROUND">The initiation of growth cessation and dormancy represent critical life-history trade-offs between survival and growth and have important fitness effects in perennial plants. Such adaptive life-history traits often show strong local adaptation along environmental gradients but, despite their importance, the genetic architecture of these traits remains poorly understood.</AbstractText><AbstractText Label="RESULTS">We integrate whole genome re-sequencing with environmental and phenotypic data from common garden experiments to investigate the genomic basis of local adaptation across a latitudinal gradient in European aspen (Populus tremula). A single genomic region containing the PtFT2 gene mediates local adaptation in the timing of bud set and explains 65% of the observed genetic variation in bud set. This locus is the likely target of a recent selective sweep that originated right before or during colonization of northern Scandinavia following the last glaciation. Field and greenhouse experiments confirm that variation in PtFT2 gene expression affects the phenotypic variation in bud set that we observe in wild natural populations.</AbstractText><AbstractText Label="CONCLUSIONS">Our results reveal a major effect locus that determines the timing of bud set and that has facilitated rapid adaptation to shorter growing seasons and colder climates in European aspen. The discovery of a single locus explaining a substantial fraction of the variation in a key life-history trait is remarkable, given that such traits are generally considered to be highly polygenic. These findings provide a dramatic illustration of how loci of large-effect for adaptive traits can arise and be maintained over large geographical scales in natural populations.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Jing</ForeName><Initials>J</Initials><Identifier Source="ORCID">0000-0002-3793-3264</Identifier><AffiliationInfo><Affiliation>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå, Sweden. jingwang368@gmail.com.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre for Integrative Genetics, Department of Animal and Aquacultural Sciences, Faculty of Life Sciences, Norwegian University of Life Sciences, PO Box 5003, Ås, Norway. jingwang368@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ding</LastName><ForeName>Jihua</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, 901 83, Umeå, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tan</LastName><ForeName>Biyue</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå, Sweden.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Stora Enso Biomaterials, 13104, Nacka, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Robinson</LastName><ForeName>Kathryn M</ForeName><Initials>KM</Initials><AffiliationInfo><Affiliation>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Michelson</LastName><ForeName>Ingrid H</ForeName><Initials>IH</Initials><AffiliationInfo><Affiliation>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Johansson</LastName><ForeName>Anna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Wallenberg Advanced Bioinformatics Infrastructure, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nystedt</LastName><ForeName>Björn</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Wallenberg Advanced Bioinformatics Infrastructure, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scofield</LastName><ForeName>Douglas G</ForeName><Initials>DG</Initials><AffiliationInfo><Affiliation>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå, Sweden.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Ecology and Genetics, Evolutionary Biology, Uppsala University, Uppsala, Sweden.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Uppsala Multidisciplinary Center for Advanced Computational Science, Uppsala University, Uppsala, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nilsson</LastName><ForeName>Ove</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, 901 83, Umeå, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jansson</LastName><ForeName>Stefan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Street</LastName><ForeName>Nathaniel R</ForeName><Initials>NR</Initials><AffiliationInfo><Affiliation>Umeå Plant Science Centre, Department of Plant Physiology, Umeå University, 90187, Umeå, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ingvarsson</LastName><ForeName>Pär K</ForeName><Initials>PK</Initials><AffiliationInfo><Affiliation>Umeå Plant Science Centre, Department of Ecology and Environmental Science, Umeå University, 90187, Umeå, Sweden. par.ingvarsson@slu.se.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Present address: Department of Plant Biology, Uppsala BioCenter, Swedish University of Agricultural Sciences, PO Box 7080, 750 07, Uppsala, Sweden. par.ingvarsson@slu.se.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2018</Year><Month>06</Month><Day>04</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Genome Biol</MedlineTA><NlmUniqueID>100960660</NlmUniqueID><ISSNLinking>1474-7596</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000222" MajorTopicYN="N">Adaptation, Physiological</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017343" MajorTopicYN="N">Genes, Plant</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D056426" MajorTopicYN="N">Genetic Loci</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014644" MajorTopicYN="N">Genetic Variation</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018745" MajorTopicYN="N">Genome, Plant</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000071421" MajorTopicYN="N">Life History Traits</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010641" MajorTopicYN="N">Phenotype</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010944" MajorTopicYN="N">Plants</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D032107" MajorTopicYN="N">Populus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Adaptive traits</Keyword><Keyword MajorTopicYN="Y">Genomic basis</Keyword><Keyword MajorTopicYN="Y">Local adaptation</Keyword><Keyword MajorTopicYN="Y">Populus tremula</Keyword><Keyword MajorTopicYN="Y">PtFT2</Keyword><Keyword MajorTopicYN="Y">Selective sweep</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>12</Month><Day>04</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2018</Year><Month>05</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2018</Year><Month>6</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2018</Year><Month>6</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2018</Year><Month>10</Month><Day>31</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">29866176</ArticleId><ArticleId IdType="doi">10.1186/s13059-018-1444-y</ArticleId><ArticleId IdType="pii">10.1186/s13059-018-1444-y</ArticleId><ArticleId 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Street</name><name sortKey="Tan, Biyue" sort="Tan, Biyue" uniqKey="Tan B" first="Biyue" last="Tan">Biyue Tan</name><name sortKey="Tan, Biyue" sort="Tan, Biyue" uniqKey="Tan B" first="Biyue" last="Tan">Biyue Tan</name></country><country name="Norvège"><noRegion><name sortKey="Wang, Jing" sort="Wang, Jing" uniqKey="Wang J" first="Jing" last="Wang">Jing Wang</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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